Date: 3 months ago   Category: Science

The way to predict death is found


Scientists of University of Auckland have found the molecular markers connected with circadian rhythms on which it is possible to predict the death of fruit flies of Drosophila melanogaster some days before death of insects. Article of researchers is published in the Scientific Reports magazine. Circadian rhythms call the fluctuations of intensity of various biological processes connected with change of day and night. It is known that the correct daily rhythm increases life expectancy of an organism and reduces risk of a disease of cancer, and violation of biorhythms, on the contrary, provokes development of age diseases. Besides, it is shown that with age the person has shifts in cycles a dream wakefulness. Circadian systems consist of a set of the interacting nervous cages oscillators. They form biological clock of an organism and are synchronized by a suprakhiazmatichesky kernel (forward area of a hypothalamus) at mammals, and at fruit flies — a cluster from about 150 neurons in which key circadian genes expressirutsya. Except these centers there are still peripheral oscillators. Scientists didn't know precisely whether aging by defects in the central biological clock or weakening of synchronization of peripheral systems is caused. Researchers have studied work of two key genes (in a brain and peripheral fabrics) ensuring functioning of circadian rhythms at fruit flies — PERIOD and TIMELESS. In an experiment insects 10-, 30-and 50-day age have been used. It has turned out that when both genes in all organism of front sights increased the activity and lost a rhythm, to the death of insects there were only four days. This correlation was observed not only at old animals, but also at rather young. The reason of failure was in peripheral systems in which the level of an expression of both genes, on the contrary, fell, and synchronization was weakened. It is more than important news in Film of Day Telegram-channel. Subscribe!

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