Date: 7 months ago   Category: Science

The gene - "zombie" protecting from cancer is found


Scientists of the Chicago university have found out that the nonfunctional gene (pseudo-gene) at elephants called by inhibitor of leukemia 6 (LIF6) is capable to destroy defective cages, preventing development of cancer. This fragment of a genome is capable to switch in an active state, beginning to code protein which destroys mitochondrions. It is reported in the press release on Phys.org. Around the world dies 17 percent of people, however at elephants incidence much less from cancer and makes less than five percent in spite of the fact that these large mammals have more cages, and the risk of development of malignant tumors at them has to be higher. It is known that in cages of elephants there are 20 copies of a gene r53 which does cages more sensitive to the damaged DNA. In new work scientists have shown that r53 are capable to activate "zombie" - LIF6 gene. Was considered that genes of the LIF family have lost ability to code protein, however, according to scientists, LIF6 has somehow revived. It is shown that he participates in destruction of a membrane of mitochondrions in cages with mutations. As a result defective cages quickly perish. Elephants have eight LIF genes, but only LIF6 is capable to become functioning. According to scientists, this ability to switching of activity has appeared about 25-30 million years ago and became a decisive factor of increase in the sizes of a body of mammals. It is more than important news in Film of Day Telegram-channel. Subscribe!

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